Registration Dossier

Administrative data

Endpoint:
relative self-ignition temperature (solids)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.16 (Relative Self-Ignition Temperature for Solids)
Version / remarks:
-
Deviations:
no
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,4-Diamino-6-chloropyrimidine-3-oxide
EC Number:
609-076-5
Cas Number:
35139-67-4
Molecular formula:
C4H5ClN4O
IUPAC Name:
2,4-Diamino-6-chloropyrimidine-3-oxide
Test material form:
solid
Remarks:
white/beige solid
Specific details on test material used for the study:
- Analytical purity: > 99%- Lot/batch No.: 0160405- Expiration date of the lot/batch: 21/02/2018

Results and discussion

Relative self-ignition temperature (solids)
Key result
Remarks on result:
no self ignition observed under the test conditions

Any other information on results incl. tables

Temperature Data

The temperatures which were measured in the experiment are presented in the following table. As more than 132 values were recorded, only the values every 60 minutes are presented.

Presentation of Temperatures versus time

Time

Temperature (oven)

in °C

Temperature (test substance)

in °C

5

22.9

22.1

60

48.4

36.7

120

85.4

68.1

180

120.3

101.9

240

155.1

138.7

290

187.1

243.6

300

191.5

183.0

360

224.3

211.0

420

260.5

248.4

480

296.1

285.8

540

332.1

322.6

600

368.4

361.2

660

401.1

399.2

 

Results

No significant variation between the temperature in the test substance and the oven temperature could be observed.

The test substanceMEXORYL SAG/10 lyophiliséis considered as not auto-flammable under the test conditions.

Applicant's summary and conclusion

Conclusions:
No significant variation between the temperature in the test substance and the oven tem-perature could be observed. The test substance MEXORYL SAG/10 lyophilisé is considered as not auto-flammable under the test conditions.
Executive summary:

The relative self-ignition temperature of the test item has been investigated with a not-GLP compliant study following the EU method A.16. No significant variation between the temperature in the test substance and the oven temperature could be observed. The test item is considered as not auto-flammable under the test conditions.