Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 807-489-7 | CAS number: 1447712-18-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The GLP conform bacterial reverse mutation assay (key_bacterial reverse mutation assay_2014_RL1) performed according to OECD 471 and
the GLP conform in vitro mammalian cell micronucleus test (key_in vitro mammalian cell micronucleus test_2015_RL1) performed according to OECD 487 showed that the test item did not induce gene mutations and is not clastogenic and not aneugenic.
Justification for selection of genetic toxicity endpoint
GLP guideline studies conducted with the test item
Short description of key information:
Bacterial reverse mutation assay/Ames test: negative (OECD 471; GLP compliant)
In vitro mammalian cell micronucleus test: negative (OECD TG 487, GLP compliant)
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Based on the guideline-conform studies conducted under GLP, the test substance should be considered void of genotoxicity. Thus, according to Directive 67/548 /EEC as amended and according to Regulation (EC) No 1272/2008 as amended, the test substance is not be considered to be genotoxic, and hence no classification or labelling is required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
