Registration Dossier

Identification

Chemical structure
Display Name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one

Type of substance

Composition:
mono-constituent substance
Origin:
organic

Other names

Trade names:
Methylprednisolone

Total tonnage band

Total range:
Intermediate Use Only

REACH

Registered as:
INTERMEDIATE
Submitted:
Joint Submission

Publication dates

First published:
30-Jan-2016
Last modified:
14-Jul-2019

Chemical safety assessment

Performed for this substance:
NO

Compositions open all close all

Type:
legal entity composition of the substance
State Form:
solid: particulate/powder


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Type:
legal entity composition of the substance
State Form:
solid: particulate/powder


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Type:
legal entity composition of the substance
State Form:
solid: particulate/powder
Degree of purity:
>= 99 - < 100 % (w/w)


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Impurity 1
Chemical structure
Reference substance name:
Methanol
EC Number:
200-659-6
EC Name:
Methanol
CAS Number:
67-56-1
Molecular formula:
CH4O
IUPAC Name:
methanol
Impurity 2
Chemical structure
Reference substance name:
Acetone
EC Number:
200-662-2
EC Name:
Acetone
CAS Number:
67-64-1
Molecular formula:
C3H6O
IUPAC Name:
Acetone
Impurity 3
Chemical structure
Reference substance name:
Dichloromethane
EC Number:
200-838-9
EC Name:
Dichloromethane
CAS Number:
75-09-2
Molecular formula:
CH2Cl2
IUPAC Name:
Methylene chloride
Type:
legal entity composition of the substance
State Form:
solid: bulk


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Type:
boundary composition of the substance
State Form:
solid: particulate/powder


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one

Registrants /Suppliers of the substance open all close all

Latest dossier received
Registrant / Supplier details 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019
CRYSTAL PHARMA SAU Parque Tecnológico, parcela 105 47151 Boecillo Valladolid Spain X
NEWCHEM S.P.A. VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy X
o RSI ChemRep Europe Ltd (P001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland X
sanofi chimie 82 avenue Raspail 94250 Gentilly France X

Administrative data open all close all

  • 01-2120093997-32-0000
  • 01-2120093997-32-0001
  • 01-2120093997-32-0002
  • 01-2120093997-32-0003

Contact Persons responsible for the SDS