Registration Dossier

Identification

Chemical structure
Display Name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one

Type of substance

Composition:
mono-constituent substance
Origin:
organic

Total tonnage band

Total range:
Intermediate Use Only

REACH

Registered as:
INTERMEDIATE
Submitted:
Joint Submission

Publication dates

First published:
30-Jan-2016
Last modified:
23-May-2020

Chemical safety assessment

Performed for this substance:
NO

Compositions open all close all

Type:
legal entity composition of the substance
State Form:
solid: particulate/powder
Degree of purity:
>= 99 - < 100 % (w/w)


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Impurity 1
Chemical structure
Reference substance name:
Methanol
EC Number:
200-659-6
EC Name:
Methanol
CAS Number:
67-56-1
Molecular formula:
CH4O
IUPAC Name:
methanol
Impurity 2
Chemical structure
Reference substance name:
Acetone
EC Number:
200-662-2
EC Name:
Acetone
CAS Number:
67-64-1
Molecular formula:
C3H6O
IUPAC Name:
Acetone
Impurity 3
Chemical structure
Reference substance name:
Dichloromethane
EC Number:
200-838-9
EC Name:
Dichloromethane
CAS Number:
75-09-2
Molecular formula:
CH2Cl2
IUPAC Name:
Methylene chloride
Type:
boundary composition of the substance
State Form:
solid: particulate/powder


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Type:
legal entity composition of the substance
State Form:
solid: particulate/powder


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Type:
legal entity composition of the substance
State Form:
solid: bulk


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Type:
legal entity composition of the substance
State Form:
solid: particulate/powder


Constituent 1
Chemical structure
Reference substance name:
Methylprednisolone
EC Number:
201-476-4
EC Name:
Methylprednisolone
CAS Number:
83-43-2
Molecular formula:
C22H30O5
IUPAC Name:
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one

Registrants / Suppliers Details open all close all

Registrant / Supplier Registered Updated
CRYSTAL PHARMA SAU Parque Tecnológico, parcela 105 47151 Boecillo Valladolid Spain 2018
NEWCHEM S.P.A. VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy 2018
RSI ChemRep Europe Ltd (P001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland 2015 2016
sanofi chimie 82 avenue Raspail 94250 Gentilly France 2017

Administrative data open all close all

  • 01-2120093997-32-0000
  • 01-2120093997-32-0001
  • 01-2120093997-32-0002
  • 01-2120093997-32-0003

Contact Persons responsible for the SDS