Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 695-949-6 | CAS number: 1187576-41-5
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
No studies on the chronic toxicity to fish are available for the members of the PFAE fumarates category. Nevertheless, the acute aquatic toxicity tests of these esters clearly showed no effects occurring in the range of water solubility in fish, Daphnia nor algae. Furthermore, only negligible releases into surface waters from sewage treatment plants are expected to take place due to: a) the rapid biodegradability and b) the high adsorption properties and low water solubility’s of these substances, resulting in an effective removal in sewage treatment plants. Therefore chronic exposure of aquatic organisms is unlikely. In addition, available data indicate that all members of the PFAE fumarates are not bioaccumulative. In addition, the ECHA Guidance on information requirements and chemical safety assessment, Chapter R.7b (ECHA, 2012b) states that “chronic fish toxicity testing is generally only necessary, when the P and B criteria are fulfilled” and this is clearly not the case. Hence due to animal welfare reasons and to avoid unnecessary vertebrate tests, no further long-term test with fish is required for any member of the PFAE fumarates category.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
