Registration Dossier
Registration Dossier
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EC number: 203-860-7 | CAS number: 111-34-2
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Meets scientific standards
Data source
Reference
- Reference Type:
- publication
- Title:
- Depletion of glutathione and hepato-toxicity caused by vinyl ethers in mice
- Author:
- Isobe M, Sone T, Takabatake E
- Year:
- 1 995
- Bibliographic source:
- J Toxicol Sci 20: 161-164
Materials and methods
- Type of study / information:
- Hepatotoxicity
- Principles of method if other than guideline:
- Hepatotoxicity in mice after i.p. injection
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Butyl vinyl ether
- EC Number:
- 203-860-7
- EC Name:
- Butyl vinyl ether
- Cas Number:
- 111-34-2
- Molecular formula:
- C6H12O
- IUPAC Name:
- 1-(ethenyloxy)butane
- Details on test material:
- butyl vinyl ether
no further data
Constituent 1
Results and discussion
Any other information on results incl. tables
No effects on hepatic non-protein sulfhydryl content.
No effects on serum glutamate pyruvate transaminase activty.
Applicant's summary and conclusion
- Conclusions:
- No hepatotoxic effects under the limited experimental conditions in this study (one dose, only 1 h post exposure observation time).
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