Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
column elution method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Details on test material:
Test item: Gonol
CAS number: 14507-49-4
Batch number: 252156N
Physical state: Solid, crystalline substance
Colour: White
Storage: At a temperature of 15 to 30 °C

Results and discussion

Water solubility
Key result
Water solubility:
325 µg/L
Conc. based on:
test mat.
Temp.:
22.5 °C
pH:
5

Applicant's summary and conclusion

Conclusions:
Preliminary phase the estimated water solubility was 0.000087 g/l. As the estimated solubility of the test item was lower than 0,01 g/l, so the column elution method was applied int he second phase of the test.
The solubility was determined at 259 and 140 ml/hour flow rates. The average water solubility of Gonol is 0.000325 g/l.