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Environmental fate & pathways

Hydrolysis

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Endpoint:
hydrolysis
Data waiving:
other justification
Justification for data waiving:
the study does not need to be conducted because the substance is readily biodegradable
Endpoint:
hydrolysis
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
QSAR prediction
Principles of method if other than guideline:
Calculation based on HYDROWIN v2.00, Estimation Programs Interface Suite™ for Microsoft® Windows v 4.11. US EPA, United States Environmental Protection Agency, Washington, DC, USA.
GLP compliance:
no
Estimation method (if used):
- Total Kb for pH > 8: 4.345E-002 L/mol sec
- Temperature for which rate constant was calculated: 25 °C
- Computer programme: HYDROWIN v2.00
pH:
7
Temp.:
25 °C
DT50:
2.632 yr
pH:
8
Temp.:
25 °C
DT50:
96.126 d
Details on results:
For detailed description on the model and its applicability, see "Any other information on materials and methods incl. tables".

Result refers to the uncharged molecule.

Description of key information

Abiotic degradation is not relevant due to ready biodegradation. 

Key value for chemical safety assessment

Additional information

No experimental studies investigating the abiotic hydrolysis of Propyleneglycol dioleate (CAS 105-62-4) are available. However, in accordance with Annex VIII, column 2 of Regulation (EC) No 1907/2006, testing is not required since the substance is readily biodegradable. In addition, a supporting QSAR calculation (HYDROWIN v2.00) indicates, that hydrolysis is a negligible pathway for the environmental fate of Propyleneglycol dioleate (CAS 105-62-4) in the environment (DT50 > 1 yr (pH 7); Werth, 2014).