Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 942-520-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 2019 - January 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- Version / remarks:
- April 4, 1984
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on preparation and application of test substrate:
- - Method of mixing into soil: The test item was mixed with industrial sand. The treated sand was mixed thoroughly with proper artificial soil. After mixing distilled water was added to adjust the moisture content to about 30 % of dry weight and the sample was mixed to be homogeneous.
- Controls: Maintanance under identical consitions without test item application. - Test organisms (species):
- Eisenia fetida
- Details on test organisms:
- TEST ORGANISM
- Common name: Earthworm
- Source: Chenggong Earthworm Raising Farm, Dongli District, Tianjin
- Age at test initiation (mean and range, SD):at least two months old with clitellum
- Weight at test initiation (mean and range, SD): 0.3350 - 0.5344 g
ACCLIMATION
- Acclimation period: 24 h
- Acclimation conditions (same as test or not):same as test - Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- yes
- Total exposure duration:
- 14 d
- Test temperature:
- 18.2 - 21.2 °C
- pH:
- 6.22 - 6.28
- Details on test conditions:
- TEST SYSTEM
- Amount of soil: 750 g
- No. of organisms per container (treatment): 10
- No. of replicates per treatment group: 4
- No. of replicates per control: 4
SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
- % sand: 70
- % sphagnum peat: 10
- % clay: 20
OTHER TEST CONDITIONS
- Photoperiod: continuous light
- Light intensity: 538-631 lux
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : mortality (days 7 and 14), body weight, soil moisture content and soil pH (start and end of treatment)
TEST CONCENTRATIONS
- Range finding study: 1000 mg/kg dw
- Test concentrations: 1000 mg/kg dw - Nominal and measured concentrations:
- Nominal: 0, 1000 mg/kg dry soil
- Reference substance (positive control):
- yes
- Remarks:
- cloracetamide, historical control
- Key result
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Key result
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Details on results:
- - Mortality at end of exposure period:
no mortality
- Changes in body weight of live adults (% of initial weight) at end of exposure period: 92.2 (controls), 92.6 (tretament group) - Validity criteria fulfilled:
- yes
- Conclusions:
- Accoring to the result, the 14d LC50 of the test item to earthworms (Eisenia foetida) was greater than nominal 1000 mg/kg dw under the test conditions.
- Executive summary:
To investigate the toxicity of the test substance to soil macroorganisms a study on earthworms was performed according to OECD Test Guideline 207. 4 replicates of 10 earthworms each were exposed in artificial soil to 1000 mg/kg dw of the test substance for 14 d ays. No mortality or abnormal signs were observed. According to the result, the 14d LC50 of the test item to earthworms (Eisenia foetida) was greater than nominal 1000 mg/kg dw under the test conditions.
Reference
Description of key information
The toxicity of the test substance to soil macroorganisms was investigated in a study on earthworms performed according to OECD Test Guideline 207. 4 replicates of 10 earthworms each were exposed in artificial soil to 1000 mg/kg dw of the test substance for 14 d ays. No mortality or abnormal signs were observed. According to the results, the LC50 (14 d) of the test item to earthworms (Eisenia foetida) was greater than nominal 1000 mg/kg dw under the test conditions.
Key value for chemical safety assessment
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 1 000 mg/kg soil dw
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.