Registration Dossier
Registration Dossier
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EC number: 942-925-0 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Zinc, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine was exposed to activated sludge of domestic sewage treatment plant in a GLP study following OECD 209. The study reported of no effects after 3 hours of exposure at the limit test concentration (EC50 > 1000 mg/L, NOEC > 1000 mg/L).
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
EC50 should read > 1,000 mg/L, the NOEC should read >= 1,000 mg/L.
The study report gives EC50 > 1,000 mg/L and NOEC = 1,000 mg/L although no effect had been determined at the limit test concentration. In the absence of an effect the NOEC should be reported as >= 1,000 mg/L. Taking into account that the water solubility of zinc, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine is low with 0.52 mg/L no effects would be expected at higher test concentrations. Concluding, the test item did not cause effects at the test concentration which is higher than the water solubility. Therefore, neither EC50 nor NOEC are relevant for PNEC derivation.
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