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EC number: 942-937-6 | CAS number: -
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- February 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, to GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (Z)-cyclododec-2-enone
- Cas Number:
- 6221-51-8
- Molecular formula:
- C12H20O
- IUPAC Name:
- (Z)-cyclododec-2-enone
- Test material form:
- other: liquid
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- ca. 48 d
Initial test substance concentration
- Initial conc.:
- ca. 30 mg/L
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Results and discussion
- Preliminary study:
- Not applicable
- Test performance:
- Cyclododecenone undergoes 81% biodegradation after 28 days in the test conditions. The 10-day window criterion is also fulfilled (24% biodegradation on day 6 and 70% on day 16).
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 81
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Executive summary:
Cyclododecenone undergoes 81% biodegradation after 28 days in the test conditions. The 10-day window criterion is also fulfilled (24% biodegradation on day 6 and 70% on day 16).
Cyclododecenone did not inhibit the intrinsic respiration of the inoculum at the test concenctraion and was therefore condiered to be non-toxic to the inoculum at the test concentration.
Thus, Cyclododenone should be regarded as readily biodegradable according to this test.
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