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Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Endpoint:
fish short-term toxicity test on embryo and sac-fry stages
Type of information:
experimental study
Adequacy of study:
key study
Cross-reference
Reason / purpose:
reference to other study
Reference
Endpoint:
fish early-life stage toxicity
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Qualifier:
according to
Guideline:
OECD Guideline 210 (Fish, Early-Life Stage Toxicity Test)
Deviations:
yes
Qualifier:
according to
Guideline:
EPA OPPTS 850.1400 (Fish Early-life Stage Toxicity Test)
Deviations:
not specified
Test organisms (species):
Pimephales promelas
Test type:
flow-through
Water media type:
freshwater
Limit test:
no
Total exposure duration:
33 d
Reference substance (positive control):
no
Key result
Duration:
33 d
Dose descriptor:
NOEC
Effect conc.:
0.001 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
length
Duration:
33 d
Dose descriptor:
LOEC
Effect conc.:
0.003 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
length
Validity criteria fulfilled:
no

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report Date:
2013

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 212 (Fish, Short-term Toxicity Test on Embryo and Sac-Fry Stages)
Deviations:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Test organisms

Test organisms (species):
Pimephales promelas

Study design

Test type:
flow-through
Water media type:
freshwater
Limit test:
no
Total exposure duration:
10 d

Test conditions

Reference substance (positive control):
no

Results and discussion

Effect concentrationsopen allclose all
Duration:
10 d
Dose descriptor:
NOEC
Effect conc.:
0.23 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
other:
Duration:
10 d
Dose descriptor:
NOEC
Effect conc.:
0.13 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
other:
Duration:
10 d
Dose descriptor:
LOEC
Effect conc.:
> 0.23 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
other:
Duration:
10 d
Dose descriptor:
LOEC
Effect conc.:
0.23 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
other:
Duration:
10 d
Dose descriptor:
EC10
Effect conc.:
> 0.23 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
other:
Key result
Duration:
10 d
Dose descriptor:
EC10
Effect conc.:
0.18 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
other:
Duration:
10 d
Dose descriptor:
EC50
Effect conc.:
> 0.23 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
other:

Applicant's summary and conclusion

Validity criteria fulfilled:
yes