Registration Dossier

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Additional information

Data on physical properties were obtained from a number of proprietary studies. These studies were generally conducted to GLP and followed standard guidelines. Data on other physical properties were obtained from a number of secondary sources. The data in these secondary sources are based on a critical evaluation of peer-reviewed data and the selected values are considered to be reliable and representative of the property under investigation. Information in the review process was documented in the introduction of the source. The use of Klimisch codes (Klimisch et al., 1997) was extended to these secondary sources and a reliability code of (2) valid with restrictions was assigned when using the authoritative secondary source. In order to supplement the experimental data QSAR values were included when reliable QSAR models were available and when the category members were within the applicability domains. 

For the physico-chemical endpoints there were clear trends across the category with increasing carbon number. This allowed data gaps to be filled by read across from category members.