Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study obtained through inquiry process; SNIF file obtained from ECHA.

Data source

Reference
Reference Type:
other: SNIF
Title:
Unnamed
Year:
1986

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
not specified
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
not specified

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
yes
Details on test solutions:
The carrier solvent was tetrahydrofuran and Arkopal N150

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
not specified
Water media type:
freshwater
Total exposure duration:
96 h

Test conditions

Reference substance (positive control):
not specified

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
100 mg/L
Details on results:
The test substance precipitated immediately at concentration >100 mg/L.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
LC50 (96h) > 100 mg/L
NOEC (96h) = 100 mg/L;
Due to its very low water solubility (see IUCLID section 4.8), the test substance is considered not to be toxic to fish under the conditions of the test.
Executive summary:

The acute toxicity of the test substance to fish has been determined in a test with Brachydanio rerio (new name: Danio rerio) according to OECD Guideline 203. The LC50 (96h) was > 100 mg/L and the NOEC (96h) was = 100 mg/L. No effects were observed in the range of the low water solubility of the test substance. Therefore, the test substance is considered not to be harmful to fish.