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EC number: 223-834-9 | CAS number: 4091-39-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD Guideline Study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 3-chlorobutan-2-one
- EC Number:
- 223-834-9
- EC Name:
- 3-chlorobutan-2-one
- Cas Number:
- 4091-39-8
- Molecular formula:
- C4H7ClO
- IUPAC Name:
- 3-chlorobutan-2-one
- Reference substance name:
- 3-Chloro-2-butanone
- IUPAC Name:
- 3-Chloro-2-butanone
- Test material form:
- other: colourless liquid
- Details on test material:
- Purity > 98% (GC).
Constituent 1
Constituent 2
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Inoculation was made using a secondary effluent of good quality collected from a
treatment plant dealing with predominantly domestic sewage. The effluent was kept
under aerobic conditions in the period between sampling and application. To prepare
the inoculum the sample was filtered through a coarse filter, the first 200 mL being
discarded. The rest of the filtrate was kept aerobic until use. The inoculum was used
on the day of collection. The number of bacteria was determined with Easicult TTC.
There were 10exp8 bacteria per litre of final volume of the test medium. - Duration of test (contact time):
- ca. 28 d
Initial test substance concentration
- Initial conc.:
- ca. 2 mg/L
Reference substance
- Reference substance:
- acetic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 71
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- The reference compound sodium acetate was biodegraded by an average of 67.5 %
by exposure day 14 and reached an average biodegradation rate of 66.0% by the
end of the 28-day exposure period.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- 3-Chlorbutanon-2 was degraded (71.6%) during the test period. Since 74.9%
biodegradation was reached within ten days of biodegradation, the criterion for ready
biodegradability was met. Thus, under the conditions of this test 3-Chlorbutanon-2
was readily biodegradable. - Executive summary:
Under the present test conditions, 3-Chlorbutanon-2 was readily biodegraded by an
average of 71.6% over the 28-day exposure period to a secondary effluent from a
domestic sewage treatment plant.
The criterion for ready biodegradability (at least 60% biodegradation was reached
within ten days of biodegradation exceeding 10%) was met.
On the other hand, the reference compound sodium acetate was biodegraded by an
average of 67.5 % by exposure day 14 and reached an average biodegradation rate
of 66.0% by the end of the 28-day exposure period, thus confirming suitability of
the secondary effluent.
The test substance did not inhibit the inoculum in the toxicity control.
In conclusion, 3-Chlorbutanon-2 was readily biodegradable under the conditions of
the' Closed Bottle Test'.
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