Registration Dossier
Registration Dossier
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EC number: 200-831-0 | CAS number: 75-01-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
In accordance to section 2 of REACH Annex XI, the study on skin sensitisation does not need to be conducted as the substance is a gas.
Migrated from Short description of key information:
The gaseous nature of vinyl chloride precludes the performance of conventional skin sensitisation studies in animals.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
There is no evidence of respiratory tract sensitisation reported in repeated exposure inhalation studies in animals.
No positive human data is available.
Migrated from Short description of key information:
Based on the available animal and human data, respiratory tract sensitisation is not expected.
Justification for classification or non-classification
The gaseous nature of vinyl chloride precludes the conduct of conventional skin sensitisation studies in animals. Therefore, classification for skin sensitisation is not applicable according to EU Directive 67/548/EEC and EU Directive 67/584/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
