Registration Dossier
Registration Dossier
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EC number: 200-831-0 | CAS number: 75-01-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
In accordance to section 2 of REACH Annex XI, the study on skin sensitisation does not need to be conducted as the substance is a gas.
Migrated from Short description of key information:
The gaseous nature of vinyl chloride precludes the performance of conventional skin sensitisation studies in animals.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
There is no evidence of respiratory tract sensitisation reported in repeated exposure inhalation studies in animals.
No positive human data is available.
Migrated from Short description of key information:
Based on the available animal and human data, respiratory tract sensitisation is not expected.
Justification for classification or non-classification
The gaseous nature of vinyl chloride precludes the conduct of conventional skin sensitisation studies in animals. Therefore, classification for skin sensitisation is not applicable according to EU Directive 67/548/EEC and EU Directive 67/584/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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