Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-831-0 | CAS number: 75-01-4
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: A review paper on physico-chemical, human toxicological and ecotoxicological properties of vinyl chloride, mentioning effect of liquid vinyl chloride on skin.
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicology Update: Vinyl Chloride.
- Author:
- Easter, M.D. and Von Burg, R.
- Year:
- 1 994
- Bibliographic source:
- J Appl Toxicol 14:301-307.
Materials and methods
Test material
- Reference substance name:
- Chloroethylene
- EC Number:
- 200-831-0
- EC Name:
- Chloroethylene
- Cas Number:
- 75-01-4
- Molecular formula:
- C2H3Cl
- IUPAC Name:
- chloroethene
Constituent 1
Results and discussion
In vivo
- Irritant / corrosive response data:
- Liquid vinyl chloride would be expected to cause frostbite injury. When placed on skin, liquid vinyl chloride may freeze tissue and produce a chemical burn as it evaporates, causing damage to the underlying tissue.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
