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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP non-guideline study, available as unpublished report, minor restrictions in design and reporting, but otherwise adequate for assessment.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1973

Materials and methods

Principles of method if other than guideline:
Not specified in OECD SIDS report
GLP compliance:
no
Test type:
other:
Limit test:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
vinyl chloride 8.6%

Test animals

Species:
rat
Strain:
Wistar
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
other: sesame oil
Doses:
50 ml/kg (4000 mg/kg)
No. of animals per sex per dose:
Not specified in OECD SIDS report
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 4 000 mg/kg bw
Mortality:
There were no mortalities.
Clinical signs:
Slight effects were noted.

Applicant's summary and conclusion