Registration Dossier
Registration Dossier
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EC number: 200-831-0 | CAS number: 75-01-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-GLP non-guideline study, available as unpublished report, minor restrictions in design and reporting, but otherwise adequate for assessment.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 973
Materials and methods
- Principles of method if other than guideline:
- Not specified in OECD SIDS report
- GLP compliance:
- no
- Test type:
- other:
- Limit test:
- yes
Test material
- Reference substance name:
- Chloroethylene
- EC Number:
- 200-831-0
- EC Name:
- Chloroethylene
- Cas Number:
- 75-01-4
- Molecular formula:
- C2H3Cl
- IUPAC Name:
- chloroethene
- Details on test material:
- vinyl chloride 8.6%
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- other: sesame oil
- Doses:
- 50 ml/kg (4000 mg/kg)
- No. of animals per sex per dose:
- Not specified in OECD SIDS report
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 4 000 mg/kg bw
- Mortality:
- There were no mortalities.
- Clinical signs:
- other: Slight effects were noted.
Applicant's summary and conclusion
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