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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP non-guideline study, available as unpublished report, minor restrictions in design and reporting, but otherwise adequate for assessment.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1973

Materials and methods

Principles of method if other than guideline:
Not specified in OECD SIDS report
GLP compliance:
no
Test type:
other:
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Chloroethylene
EC Number:
200-831-0
EC Name:
Chloroethylene
Cas Number:
75-01-4
Molecular formula:
C2H3Cl
IUPAC Name:
chloroethene
Details on test material:
vinyl chloride 8.6%

Test animals

Species:
rat
Strain:
Wistar
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
other: sesame oil
Doses:
50 ml/kg (4000 mg/kg)
No. of animals per sex per dose:
Not specified in OECD SIDS report
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 4 000 mg/kg bw
Mortality:
There were no mortalities.
Clinical signs:
other: Slight effects were noted.

Applicant's summary and conclusion