Registration Dossier
Registration Dossier
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EC number: 263-467-1 | CAS number: 62229-08-7
Endpoint summary
Administrative data
Description of key information
Animal data were found indicating that lead oxide, lead phosphite and dibasic lead phthalate are not sensitising for the skin. In addition, in view of the lack of toxicity, irritation or reports of sensitisation from occupational exposure settings, lead and sparingly soluble lead compounds do not appear to pose risk of sensitisation and classification for these endpoints is not indicated.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Animal data were found indicating that lead oxide, lead phosphite and dibasic lead phthalate are not sensitising for the skin. In addition, in view of the lack of toxicity, irritation or reports of sensitisation from occupational exposure settings, lead and sparingly soluble lead compounds do not appear to pose risk of sensitisation and classification for these endpoints is not indicated.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
Animal and human data specifically evaluating lung sensitisation were not found. In view of the lack of toxicity, irritation or reports of sensitisation from occupational exposure settings, lead and sparingly soluble lead compounds do not appear to pose risk of sensitisation and classification for these endpoints is not indicated.
Justification for classification or non-classification
Animal and human data specifically evaluating lung sensitisation were not found. Animal data were found indicating that lead oxide, lead phosphite and dibasic lead phthalate are not sensitising for the skin. In addition, in view of the lack of toxicity, irritation or reports of sensitisation from occupational exposure settings, lead and sparingly soluble lead compounds do not appear to pose risk of sensitisation and classification for these endpoints is not indicated.
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