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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Description of key information

OECD Guideline 222 Earthworm (Eisenia fetida), Effects on Reproduction 

Key value for chemical safety assessment

Long-term EC10, LC10 or NOEC for soil macroorganisms:
125 mg/kg soil dw

Additional information

Under the conditions of this study,Tetraethylenepentamine, TEPAdid not induce significant mortality, pathological symptoms or changes of the behaviour of adult earthworms after 28 days of exposure at all tested concentrations.The adult earthworm biomass increased in the control and atall test item concentrationswithout any statistically significant differences.After a further four weeks of exposure the numbers of juvenile earthworms were statistically significantly lower at the test item concentrations 250, 500 and 1000 mg test item/kg soil dry weight than in the untreated control.


Thus,theNo Observed Effect Concentration(NOEC) ofTetraethylenepentamine, TEPAsummarizing the endpointsmortality, growth and reproduction ofEisenia fetidaafter eight weeks of exposure in artificial soil was determined to be 125 mg test item/kg soil dry weight.The EC10-value for reproduction was determined to be 167 mg test item/kg soil dry weight and the EC20-value was 360 mg test item/kg soil dry weight.