Registration Dossier

Administrative data

Description of key information

Instead of conducting new tests with the substance, available data on the constituents of the reaction mass of calcium carbonate, calcium dihydroxide and silicon dioxide were used to evaluate the corrosive/irritating potential of the substance. Whereas no data is available showing an irritating or corrosive potency of calcium carbonate or silicon dioxide, several sources confirmed that calcium hydroxide is to be considered irritating to the skin and respiratory tract and corrosive to the eyes.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Instead of conducting new tests with the substance, available data on the constituents of the reaction mass of calcium carbonate, calcium dihydroxide and silicon dioxide were used to evaluate the corrosive/irritating potential of the substance. Whereas no data is available showing an irritating or corrosive potency of calcium carbonate or silicon dioxide, several sources confirmed that calcium hydroxide is to be considered irritating to the skin and respiratory tract and corrosive to the eyes.

 

Information sources:

European chemical Substances Information System http://ecb.jrc.ec.europa.eu/esis/

International Programme on Chemical Safety, Concise international chemical assessment document No.24, Crystalline silica, Quartz, 09-21-10, http://www.inchem.org/documents/cicads/cicads/cicad24.htm

International chemical Safety Cards, National Instutute for occupational Safety and Health http://www.cdc.gov/niosh/ipcsneng/neng0808.html

International chemical Safety Cards, National Instutute for occupational Safety and Health http://www.cdc.gov/niosh/ipcsneng/neng0408.html

International chemical Safety Cards, National Instutute for occupational Safety and Health 

http://www.cdc.gov/niosh/ipcsneng/neng0409.html

Recommendation from the Scientific Committee on Occupational Exposure Limits for Calcium oxide (CaO) and Calcium Hydroxide (Ca(OH)2), European Commission, DG Employment, social Affairs and Equal Opportunities, SCOEL/SUM/137, February 2008

Threshold Limit Values & Biological Exposure Indices for Chemical Substances and Physical Agents, ACGIH®, Signature Publications, 2010


Effects on skin irritation/corrosion: irritating

Effects on eye irritation: corrosive

Effects on respiratory irritation: irritating

Justification for classification or non-classification

 The typical concentration of calcium dihydroxide is 38%. Considering that calcium hydroxide warrants a classification as corrosive to eyes and irritant to the skin and respiratory tract the following classification of the reaction mass of calcium carbonate, calcium dihydroxide and silicon dioxide is considered justified:

- Eye damage cat. 1 (H318 – Causes serious eye damage)

- Skin irritation cat. 2 (H315- Causes skin irritation)

- STOT SE 3 (H335 – May cause respiratory irritation)