Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Basic toxicokinetics

Currently viewing:

Administrative data

Endpoint:
basic toxicokinetics
Type of information:
other: theoretical approach
Adequacy of study:
key study
Study period:
August-September 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP assessment report; study is based on expert judgment.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010

Materials and methods

Objective of study:
toxicokinetics
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
A theoretical approach of the toxicokinetic properties of the substance based on the available physico-chemical properties and toxicological data.
GLP compliance:
no

Test material

Constituent 1
Details on test material:
- Name of test material (as cited in study report): Lowinox® TBM6
- Chemical name: 6,6’–di-tert-butyl-4,4’–thiodi-m-cresol
- Molecular formula: C22H30O2S
- Molecular weight: 358.54
- Substance type: White crystalline fine powder
- Physical state: solid
- Analytical purity: Minimum 98%

Results and discussion

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): bioaccumulation potential cannot be judged based on study results
For risk assessment purposes the following absorption factors were derived:
oral absorption factor: 50%
dermal absorption factor: 20%
inhalation absorption factor: 50%