Registration Dossier
Registration Dossier
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EC number: 940-514-0 | CAS number: -
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (LLNA)
- Data waiving:
- other justification
- Justification for data waiving:
- other:
- Justification for type of information:
- See data from the approved study plan.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
- GLP compliance:
- yes
- Type of study:
- mouse local lymph node assay (LLNA)
Test material
- Reference substance name:
- Pyrolysis light oil from waste plastics
- EC Number:
- 940-514-0
- Molecular formula:
- Not required for a UVCB-substance (mixture of multiple (>100) organic substances)
- IUPAC Name:
- Pyrolysis light oil from waste plastics
- Test material form:
- liquid: volatile
Constituent 1
In vivo test system
Test animals
- Species:
- mouse
- Strain:
- CBA/Ca
- Sex:
- female
- Details on test animals and environmental conditions:
- TEST ANIMALS
- Source: AnLab Prague, Czech Republic
- Females (if applicable) nulliparous and non-pregnant: yes
- Age at study initiation: 8-12 weeks
- Weight at study initiation:
- Housing: polycarbonate IVC cages (5 animals per cage) in a room equipped with cenrtal air-conditoning.
- Diet (e.g. ad libitum): ad libitum
- Water (e.g. ad libitum): ad libitum
- Acclimation period: 5 days
- Indication of any skin lesions: No
ENVIRONMENTAL CONDITIONS
- Temperature (°C): Room temperature
- Humidity (%): 30% - 70%
- Air changes (per hr): Not specified
- Photoperiod (hrs dark / hrs light): 12/12
Study design: in vivo (LLNA)
- No. of animals per dose:
- 5 animals per concentration
- Positive control substance(s):
- hexyl cinnamic aldehyde (CAS No 101-86-0)
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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