Registration Dossier
Registration Dossier
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EC number: 940-514-0 | CAS number: -
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity: Fixed Dose Procedure)
- GLP compliance:
- yes
- Test type:
- fixed dose procedure
- Limit test:
- yes
Test material
- Reference substance name:
- Pyrolysis light oil from waste plastics
- EC Number:
- 940-514-0
- Molecular formula:
- Not required for a UVCB-substance (mixture of multiple (>100) organic substances)
- IUPAC Name:
- Pyrolysis light oil from waste plastics
- Test material form:
- liquid: volatile
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- female
Administration / exposure
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 2000 mg/kg bw
Results and discussion
Effect levels
- Key result
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Clinical signs:
- other:
- Body weight:
- lower than 10% body weight loss
- Remarks:
- For the first day after dose application, there was a slight body weight loss in all rats on the mean value of 7.5%.
Applicant's summary and conclusion
- Interpretation of results:
- Category 5 based on GHS criteria
- Remarks:
- In the absence of deaths and evident toxicity on application dose of 2000 mg/kg body weight, the test item NAPHTHA was classified in Category5/Unclassified with a LD50 cut off value equal to or greater than 2000 mg/kg body weight according to GHS criteria for acute dermal toxicity
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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