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Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report date:
1988

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: EU Method C10: Abiotic Degradation: Hydrolysis as a function of pH
Deviations:
no
Remarks:
- The study was conducted according to the test guidelines in effect at the time of study conduct.
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
bis(4-fluorophenyl)methyl(4H-1,2,4-triazol-4yl-methyl)silane
EC Number:
600-198-4
Cas Number:
101377-47-3
Molecular formula:
C16H15N3F2Si
IUPAC Name:
bis(4-fluorophenyl)methyl(4H-1,2,4-triazol-4yl-methyl)silane
Details on test material:
- Purity: R7623 Technical, solid
Radiolabelling:
no

Study design

Analytical monitoring:
yes
Duration of testopen allclose all
Duration:
5 d
pH:
4
Initial conc. measured:
48 mg/L
Duration:
5 d
pH:
7
Initial conc. measured:
45 mg/L
Duration:
5 d
pH:
9
Initial conc. measured:
46.4 mg/L

Results and discussion

Transformation products:
not measured
Total recovery of test substance (in %)open allclose all
% Recovery:
96
pH:
4
Temp.:
50 °C
Duration:
5 d
% Recovery:
99
pH:
7
Temp.:
50 °C
Duration:
5 d
% Recovery:
88
pH:
9
Temp.:
50 °C
Duration:
5 d

Any other information on results incl. tables

% recovery values for R7623 are given in above section.

% recovery values for H6573 are below:

pH 4 = 92%

pH 7 = 98%

pH 9 = 89%

Applicant's summary and conclusion

Conclusions:
Hydrolytically stable
Executive summary:

The hydrolysis of R7623 Technical (components R7623 and H6573separately) as a function of pH was determined. At pH 4, 7 and 9, no significant hydrolysis was observed during a 5 day test at approximately 50 ºC. Hence, it was concluded that R7623 Technical is hydrolytically stable under the conditions tested.