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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Description of key information

The determination of the potential for bioaccumulation follows Guidance on Information Requirements and Chemical Safety Assessment Chapter R.16: Environmental Exposure Estimation (ECHA, 2012). Chapter R.16 and REACH Annex IX states that there may be bioaccumulation potential if log Kow is >3. Experimentally measured log Kow for Hydrotropes Category substances range between -3.18 to 0.07. The likelihood of bioaccumulation is very low and the requirement for further testing is waived.


The substance is not bioaccumulative.


The BCF value has been estimated with BCFBAF v3.01 and for all substances the Log BCF from regression-based method = 0.500 (BCF = 3.162 L/kg wet-wt). This value has been use for the Chemical safety assessment

Key value for chemical safety assessment

BCF (aquatic species):
3.162 L/kg ww

Additional information

Determination of the potential for bioaccumulation follows Guidance on Information Requirements and Chemical Safety Assessment Chapter R.16: Environmental Exposure Estimation (ECHA, 2012). Chapter R.16 and REACH Annex IX states that there may be bioaccumulation potential if log Kow is >3. Experimentally measured log Kow for Hydrotrope Category substances range between -3.18 to 0.07. The likelihood of bioaccumulation is very low and the requirement for further testing is waived.

In addition, experimental studies carried out in accordance with OECD Guideline 305C were considered to be reliable (Klimisch 2) in the evaluation of two hydrotrope category substances by the OECD SIDS SIAM Report (2006) authors. Using freshwater cyprinus species fish, the flow-through aquatic test determined bioconcentration factors from both experiments to be <2.3. The requirement for bioaccumulation testing in the aquatic environment (REACH Annex IX) is waived based on the weight of evidence from the measured Log Kow values (between -3.18 and 0.07) and the two bioaccumulation in fish studies with reported BCF of less than 2.3. The likelihood of bioaccumulation is considered to be very low.