Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Repeated dose toxicity: inhalation

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Administrative data

Endpoint:
sub-chronic toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Publication from 1955, which lacks detailed description of the test substance, study method, animal conditions and results. Examinations were limited and not according to present guidelines.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1955

Materials and methods

Test guideline
Qualifier:
no guideline followed
Deviations:
not applicable
Principles of method if other than guideline:
Rats were exposed to dust of 25 mg/m3 testsubstance for 14.5 months (100 hours/month); rabbits were exposed to dust of 31 mg/m3 testsubstance for 10 months (100 hours/month). Lungs were analyzed for their antimony content.

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion