Registration Dossier
Registration Dossier
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EC number: 203-398-6 | CAS number: 106-44-5
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Effects of phenolic smoke condensates and their components on hepatic drug metabolizing systems
- Author:
- Sternitzke A, Legrum W, Netter KJ
- Year:
- 1 992
- Bibliographic source:
- Fd Chem Toxic 30, 771-781
- Reference Type:
- publication
- Title:
- Ueber die Wirkung der Cresole und des Liquor Cresoli Saponatus im Vergleich zur Carbolsaeure
- Author:
- Tollens K
- Year:
- 1 905
- Bibliographic source:
- Arch Exp Path Pharm 52, 220-241
Materials and methods
- Principles of method if other than guideline:
- other
- GLP compliance:
- not specified
Test material
- Reference substance name:
- p-cresol
- EC Number:
- 203-398-6
- EC Name:
- p-cresol
- Cas Number:
- 106-44-5
- Molecular formula:
- C7H8O
- IUPAC Name:
- p-cresol
- Details on test material:
- Test substance: p-cresol, no further data
Constituent 1
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- subcutaneous
Results and discussion
Effect levels
- Dose descriptor:
- LC50
- Effect level:
- 150 mg/kg bw
Any other information on results incl. tables
no data
Applicant's summary and conclusion
- Executive summary:
Mice received a single subcutaneous injection of p-cresol. A LD50 = 150 mg/kg bw was determined.
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