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Environmental fate & pathways

Monitoring data

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Administrative data

Endpoint:
monitoring data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Documented analytical method. No GLP.
Cross-reference
Reason / purpose:
reference to same study

Data source

Reference
Reference Type:
publication
Title:
Liquid chromatographioc determination of melamine in beverages
Author:
Ishiwata H, Inoue T, Yamazaki T, Yoshihira K.
Year:
1987
Bibliographic source:
Journal of the Association of Offícal Analytical Chemists, 70, 457-460.

Materials and methods

Principles of method if other than guideline:
Determination of melamine in extraction media.
GLP compliance:
not specified
Media:
food

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Applicant's summary and conclusion

Executive summary:

A liquid chromatographic method is described for the determination of melamine in beverages. Melamine is separated by column chromatography using cation and anion exchange resin and determined by ion-pair liquid chromatography using an ODS column and a mixture of acetonitrile and 0.05M phosphate buffer (pH 3.0) containing 0.005M sodium 1-laurylsulfate (1 + 4, v/v) as mobile phase. Recoveries of melamine ranged between 90.3 +/- 7.8 and 102.1 +/- 5.6% at levels of 0.6 to 2.4 ppm in 4 kinds of beverages. The quantitation limit was 2.5 micrograms melamine in 50 mL beverage. The method was applied to the migration test of melamine from melamine-formaldehyde resin products to the beverages.