Registration Dossier
Registration Dossier
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EC number: 204-065-8 | CAS number: 115-10-6
Endpoint summary
Administrative data
Description of key information
This substance is a gas and guideline testing for skin sensitisation is technically not feasible.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
This substance is a gas and guideline testing for skin sensitisation is technically not feasible.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
At present, recognised and validated animal models for the testing of respiratory sensitization are not available. The molecular structure of DME provides no indication for such a concern. Repeated inhalation studies in animals, as well as experience in humans, have not provided any indication of possible respiratory sensitization by DME.
Justification for classification or non-classification
There is no evidence of respiratory sensitization during inhalation exposures. The substance does not need to be classified for skin or respiratory sensitization according the EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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