Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-313-2
CAS number: 105-60-2
Table 1: Mortality of males and females.
This study was performed similar to the OECD guideline 403.
Rats were exposed to a liquid aerosol of the test substance using a
head-nose inhalation system at analytical concentrations of 5.25, 8.35
and 10.12 mg/l for 4 hours. Exposure related mortalities were observed
at all dose levels and the LC50 for male/female was determined to be
Observed clinical signs of toxicity were indicative for
irritation (eyelid closure, irregular respiration, escape reaction
during exposure and dyspnoea, piloerection, bloody nose and eye
discharge and tremor after exposure). Clinical signs were reversible
with 7 days post exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again