Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 247-655-0
CAS number: 26399-02-0
No acute toxicity effects up to the limit of water solubility.
There are no studies available on the short-term toxicity of 2
-ethylhexyl oleate (CAS 26399 -02 -0) to freshwater fish. The assessment
was therefore based on studies conducted with the category members Fatty
acids, C16-18 and C18-unsatd., 2-ethylhexyl esters (CAS 85049-37-2) and
Fatty acids, C8-16, 2-ethylhexyl esters (CAS 135800-37-2), as part of a
read across approach, which is in accordance with Regulation (EC) No.
1907/2006, Annex XI, 1.5. Grouping of substance and read across
approach. Further justification is given within the endpoint summary 6.1
and within the category justification section 13. In this case of
read-across, the best suited (highest degree of structural similarity,
nearest physico-chemical properties) read-across substance was entered
into IUCLID. Nevertheless, as can be seen in the data matrix of the
category justification in Section 13, all reliable data in the category
support the hazard assessment for this endpoint, by showing a consistent
pattern of results.
In the selected read-across study with Fatty acids, C16-18 and
C18-unsatd., 2-ethylhexyl esters (CAS 85049-37-2) the acute toxicity to
Danio rerio was tested according to OECD 203 with nominal concentrations
of 1000, 3000 and 10000 mg/L. The test substance was directly added into
the test medium and tested as an emulsion. No mortality was observed up
to the highest test concentration and an LC50(96h) > 10000 mg/L could be
stated (Richterich 2001).
In another read-across from Fatty acids, C8-16, 2-ethylhexyl
esters (CAS 135800-37-2), the marine species Scopthalmus maximus was
tested with a WAF, resulting in a nominal LL50(96h) value > 5600 mg/L
Additionally, a marine fish study is available for 2 -ethylhexyl
oleate. The study was conducted according to OECD Guideline 203, using
Scopthalmus maximus as test organism (Craig, 2002). No mortality
occurred during the test, and the LC50 was determined to be > 1800 mg/L.
Thus, based on the above mentioned result, and due to the
structural and profile similarities of the substances, as are explained
with in the overall endpoint summary 6.1 it can be concluded that no
toxicological effects on fish are expected up to the limit of water
solubility for 2 -ethylhexyl oleate (CAS 26399 -02 -0).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again