Registration Dossier
Registration Dossier
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EC number: 807-645-4 | CAS number: 701920-77-6
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
PBT Assessment DBEESU
The PBT Assessment for Bis(2-(2-butoxyethoxy)ethyl) succinate (CAS 701920-77-6) is based on the criteria set out in the “Guidance on information requirements and chemical safety assessment, Chapter R.11: PBT Assessment” (ECHA, 2012).
Persistence
Bis(2-(2-butoxyethoxy)ethyl) succinate (CAS 701920-77-6) is readily biodegradable according to BIOWIN v4.10 . Thus, the substance does not meet the screening criterion for persistence and is not considered to be P or vP.
Bioaccumulation
Due to the rapid environmental biodegradation and metabolism via enzymatic hydrolysis of Bis(2-(2-butoxyethoxy)ethyl) succinate, a relevant uptake and bioaccumulation in aquatic organisms is not expected. Enzymatic breakdown will initially lead to the free fatty acid and the corresponding alcohol. This is supported by the low calculated BCF value 3.14 L/kg ww (BCFBAF v3.01, Arnot-Gobas, including biotransformation, upper trophic). The log ko/w= 2.25. Thus, the test substance does not meet the criterion for bioaccumulative and it is not considered to be B or vB.
Toxicity
Bis(2-(2-butoxyethoxy)ethyl) succinate is not classified according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008.
Bis(2-butoxyethyl) succinate does not fulfill the T criterion: the substance
- exerts no long-term toxicity to aquatic organisms (NOEC > 0.01 mg/l)
- is not classified as carcinogenic, germ cell mutagenic or toxic for reproduction
- is not classified for chronic toxicity (R48) or specific organ toxicity (STOT )
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