Registration Dossier
Registration Dossier
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EC number: 939-698-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Skin irritation (OECD 404): not irritating
Eye irritation (OECD 405): corrosive
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin irritation
One key study is available investigating the skin irritating potential of Decyl glucoside in 1 female and 2 male rabbits according to OECD guideline 404 (BASF, 1982). No skin reactions were observed during the 8-day observation period. Based on these results, the test substance may not be considered to be a skin irritant.
Eye irritation
One reliable study on the eye irritating potential of Decyl glucoside according to OECD guideline 405 exists, in which the undiluted test material was placed into the respective eye of 1 male and 2 female rabbits (BASF, 1982). The other eye remained untreated and served as control. The eyes were examined and scored 1, 24, 48 and 72 h after application. Test substance instillation into the rabbit eye induced iridial, corneal and conjunctival effects. These effects were not reversible in most of the animals within a 15-day observation period. Based on these results, the test substance may be considered to cause serious damage to the eye.
Respiratory tract
This information is not available and not mandatory according to Regulation (EC) No. 1907/2006.
Justification for selection of skin irritation / corrosion endpoint:
There is only one study available.
Justification for selection of eye irritation endpoint:
There is only one study available.
Effects on eye irritation: corrosive
Justification for classification or non-classification
The available data on skin irritation of Reaction products of D-Glucose, n-Butanol and C10-12 (even numbered) alcohols do not meet the criteria for classification according to Regulation (EC) No 1272/2008 or Directive 67/548/EEC, and are therefore conclusive but not sufficient for classification. The available data on eye irritation of Reaction products of D-Glucose, n-Butanol and C10-12 (even numbered) alcohols meet the criteria for classification as Eye Dam. 1 (H318) according to Regulation (EC) No 1272/2008 and Xi (R41) according to Directive 67/548/EEC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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