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Classification & Labelling & PBT assessment

PBT assessment

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PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB
Justification:

The PBT Assessment for Reaction products of D-Glucose, n-Butanol and C10-12 (even numbered) alcohols is based on the criteria set out in the “Guidance on information requirements and chemical safety assessment, Chapter R.11: PBT Assessment” (ECHA, 2008).

Persistence

Screening criteria:

Reaction products of D-Glucose, n-Butanol and C10-12 (even numbered) alcohols is readily biodegradable in a study according to OECD 301B (70 -80% (CO2 evolution) after 28 d). Thus, the substance does not meet the screening criterion for persistence and it is not considered to be persistent (P) or very persistent (vP).

Bioaccumulation

Screening criteria:

Reaction products of D-Glucose, n-Butanol and C10-12 (even numbered) alcohols exhibits log Pow values <=2.9 (worst-case QSAR, KOWWIN). Thus, the substance does not meet the screening criterion for bioaccumulation and is not considered to be bioaccumulative (B) or very bioaccumulative (vB).

Toxicity

Long-term toxicity testing with Daphnia magna resulted in an EC10 value of 1.76 mg a.i./L for the category member D-Glucopyranose, oligomeric, C10 -C16 -alkyl glycosides (OECD 202 part II). Moreover, the substance is not classified according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (2nd ATP). Thus, the criteria set out in Annex XIII of Regulation (EC) No. 1907/2006 are not met and the test substance is not considered to meet the T criterion.