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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1977
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
no
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
not specified
Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Details on test organisms:
TEST ORGANISM
- Common name: Zebra fish
Test type:
not specified
Water media type:
not specified
Limit test:
no
Total exposure duration:
48 h
Test temperature:
15 °C
pH:
8.3
Nominal and measured concentrations:
Concentrations: 1000 mg/ml
Reference substance (positive control):
no
Duration:
48 h
Dose descriptor:
other: TL0
Effect conc.:
1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Remarks on result:
other:
Remarks:
No Mortality was observed
Duration:
48 h
Dose descriptor:
other: TL50
Effect conc.:
1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Remarks on result:
other:
Remarks:
No Mortality was observed
Duration:
48 h
Dose descriptor:
other: TL100
Effect conc.:
1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Remarks on result:
other:
Remarks:
No Mortality was observed
Validity criteria fulfilled:
not specified
Conclusions:
The TL50 of test substance was 1000 mg/l
Executive summary:

The study was conducted with FAT 36034/A at concentration of 1000 mg/l using 8 fish per concentration. Temperature and pH was 15°C and 8.3 respectively. There were no mortality found at these dose level.

So, the TL50 of test substance was 1000 mg/l.

The above threshold limit values for FAT 36034/A shows that the test item does not cause acute toxicity to fish.

Description of key information

Data on short term toxicity to fish study ware not available for the target substance. To fill the data gap, read across is performed using similar substance FAT 36034/A. Read-across is claimed basis of structural relationship of the target and the source chemicals.

The study with FAT 36034/A was conducted at a concentration of 1000 mg/l using 8 fish per concentration. Temperature and pH was 15 °C and 8.3 respectively. There was no moratlity found at this dose level. So, the TL50 of test substance was defined to be >1000 mg/l.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Additional information