Registration Dossier
Registration Dossier
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EC number: 287-636-4 | CAS number: 85566-26-3
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Fatty acids, C8-10, Me esters (CAS 85566-26-3) is not bioaccumulative.
Key value for chemical safety assessment
Additional information
In contrast to a log KOW of > 3 for Fatty acids, C8-10, Me esters (CAS 85566-26-3), a Fatty Acid Methyl Esters with carbon chain length C8 - C10, no bioaccumulation potential is expected.
Due to the low water solubility and the ready biodegradability of Fatty acids, C8-10, Me esters (CAS 85566-26-3) the bioavailability is very low and an uptake is not expected. Should the substance be taken up by fish, Fatty Acid Methyl Ester will be extensively metabolized by carboxylesterase (CaEs) enzymes, which are ubiquitous across species and have a broad specificity. Aliphatic esters, like Fatty Acid Methyl Esters, are biotransformed into fatty acids that are very similar to endogenous compounds and are rapidly used as carbon and energy sources. In addition, existing experimental fish bioconcentration data (42-day laboratory study, OECD 305) for aliphatic esters with log Kow between 3 and 6 show BCF values below 100, which is indicating no bioaccumulation potential. More detailed information can be found attached in the bioaccumulation assessment in IUCLID 5.2 under chapter 13.
In conclusion, Fatty Acid Methyl Esters are non-bioaccumulative.
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