Registration Dossier
Registration Dossier
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EC number: 284-325-5 | CAS number: 84852-15-3
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- other: poisoning incident
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- This publication summarizes poisoning incidents of chemically induced vitiligo (leucoderma) caused by alkylated phenols and catechols. No specific data for Nonylphenol are provided; NP is referenced only as being mentioned in a case report published by Ikeda et al. 1970.
Data source
Reference
- Reference Type:
- publication
- Title:
- Environmentally induced vitiligo (Leucoderma) from depigmenting agents and chemicals
- Author:
- Stevenson, C.J.
- Year:
- 1 984
- Bibliographic source:
- J. Toxicol.- Cut. & Ocular Toxicol. 2(3), 299-307
Materials and methods
- Study type:
- poisoning incident
- Endpoint addressed:
- skin irritation / corrosion
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- no
Test material
- Reference substance name:
- Alkylphenol
- IUPAC Name:
- Alkylphenol
Constituent 1
Method
- Type of population:
- occupational
- Route of exposure:
- dermal
- Reason of exposure:
- intentional, occupational
- Exposure assessment:
- not specified
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
