Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
- Principles of method if other than guideline:
- OECD guideline 105 was not appropriate and the cloud point technique was used to determine the solubility of the test substance in water. Solubility was defined as the weight of the test substance that resulted in a non-cloudy solution.
- GLP compliance:
- yes
Test material
- Details on test material:
- - Purity: not reported as such
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 2.1 g/L
- Temp.:
- 26 °C
- pH:
- >= 4 - <= 9
- Details on results:
- pH was not measured, but is expected to be in the environmentally relevant range of pH 4-9, as defined in OECD 111, since there are no functional groups present on the compounds in the mixture that would have a significant impact on the pH. Only the first vial yielded a clear solution on visual inspection, therefore according to this approach the solubility in water was determined to be 2.1 g/L at 26°C for the bulk test substance.
Applicant's summary and conclusion
- Conclusions:
- solubility in water = 2.1 g/L at 26°C
- Executive summary:
To determine the solubility at 26°C aliquots of test substance (0.0210, 0.0397, and 0.0610 g) were weighed into three separate vials. A 10 mL aliquot of deionised water was added to each vial. These vials were placed on a shaker at 26°C for 16 hours. The samples were then visually analysed for signs of saturation (i.e., turbidity or increased viscosity). The solubility was determined to be the last sample concentration that did not show signs of saturation. Only the first vial yielded a clear solution on visual inspection, therefore according to this approach the solubility in water was determined to be 2.1 g/L at 26°C for the bulk test substance.
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