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EC number: 200-193-3 | CAS number: 54-11-5
The test item nicotine was tested using a concentration of at least 20 mg organic carbon/L (corresponding to 27.0 mg nicotine/L) in test medium following OECD 301B and EU-Method C.4-C.
Aniline was chosen as positive control.
Activated sludge was used as inoculum (concentration in the test 25.0 mg dry matter/L). The test was left running for 28 days.
All validity criteria were met. Degradation of the positive control was 71% after seven days.
The following data were determined for the test item nicotine:
10-day-window: day 3 – 13 degradation at the end of 10-day-window: 72%
degradation at the end of the test: 71%
pass level following guideline: 60% at the end of 10-day-window
No inhibition of the degradation of the reference substance was observed in the toxicity control of this test in the presence of 27 mg/L.
One key study of high quality is available (Klimisch 1). The study is GLP compliant and appropriate for risk assessment, therefore no further testing is needed.
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