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Physical & Chemical properties

Flash point

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Reference
Endpoint:
flash point of flammable liquids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2014-09-22 to 2014-09-24
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was performed in accordance with standard test protocols (EU A.9, OPPTS 830.6315, and UN Manual Test Methods 32.4) in a quality controlled laboratory. The study is valid according to criteria mentioned in the test protocols.
Qualifier:
according to
Guideline:
EU Method A.9 (Flash-Point)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.6315 (Flammability)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
non-equilibrium method closed cup
Flash point:
111 °C
Atm. press.:
101.325 kPa

In a safety test, ca. 3 mL of the test item nicotine were heated in a test tube with a Bunsen burner to the boiling temperature (approximately 270 °C). Thereby, the light yellowish colour became stronger. After cooling down, no further changes of the test item were observed.

In the following pre-test and main study, about 70 mL of the liquid test item nicotine were used, respectively. Each determination was performed with a fresh aliquot of the test item.

The following program parameters were applied:

Determination

Heating Rate

Ignition Attempt

pre-test

8.5 °C/min

every 5 °C

main study

5.5 °C/min

every 2 °C,

starting 22 °C below expected flash point

The following results were obtained:

Determination

Flash point
[°C]

Mean
[°C]

Notes

pre-test

115.5

 

not used for calculation

main study

111.5

111.0

difference < 2 °C

main study

110.5

Conclusions:
The flash point corresponds to the mean value of two determinations and amounts to 111.0 ± 0.5 °C (384.2 ± 0.5 K). The difference between the two measured values was below 2 °C. For this reason, the determination is considered valid.
Executive summary:

First, a safety test was performed: ca. 3 mL of the test item nicotine were heated to the boiling point of approximately 270 °C. Thereby, the light yellowish colour became more intensive, but no signs of polymerisation or decomposition were observed.

Then, a pre-test and a main study with two experiments were performed with a flash point tester.

The flash point of nicotine is stated as 111.0 ± 0.5 °C (384.2 ± 0.5 K).

This value is the mean of two independent determinations.

Description of key information

Study was conducted in a quality controlled laboratory. The results are reliable without restriction. Key study is appropriate for the risk assessment.

Key value for chemical safety assessment

Flash point at 101 325 Pa:
111 °C

Additional information