Registration Dossier

Toxicological information

Genetic toxicity: in vivo

Currently viewing:

Administrative data

Endpoint:
in vivo mammalian germ cell study: gene mutation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
secondary source
Title:
Toxicological Profile for carbon disulfide
Author:
U.S. Department of Health and Human Services
Year:
1996
Bibliographic source:
U.S. Department of Health and Human Services . Public Health Service . Agency for Toxic Substances and Disease Registry

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)
Deviations:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent

Test animals

Species:
Drosophila melanogaster

Administration / exposure

Route of administration:
oral: unspecified
Doses / concentrations
Remarks:
Doses / Concentrations:200 – 1000 ppm Basis:no data

Results and discussion

Test results
Genotoxicity:
negative

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): negative