Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The 24-hours EC50 for IPC in Daphnia magna was reported to be 245 - 347 mg/L.

Daphnia magna: EC50 (24 hrs) = 245 - 347 mg/L

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
245 mg/L

Additional information

IPC was reported to have a 24 hour EC50 of 245 mg/L in Daphnia magna (Thun, 1990). The study was conducted under GLP and according to OECD Guideline 202; however, purity and the source of the substance were not reported, and the exposure period was 24 hours rather than 48 hours. The study was performed in a static system. Because of the characteristics of the results for the main test, it was more appropriate to give a range for the 24 h EC50: 360 mg/L<EC50<510 mg/L. These values are based on the initial concentrations of the test article. If the average effective concentration (68% of the initial test article concentration) is used as a basis, the EC50 can be corrected as follows: 245 mg/L<EC50<347 mg/L.