Registration Dossier
Registration Dossier
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EC number: 939-200-6 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96-hour NOEC for fish was found to be 100 mg/L and the EC50 was found to be >100 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
An OECD 203 acute fish toxicity test was conducted for sodium isobutyrate solution. The test duration was 96 hours under semi-static conditions, with renewal of the test media every 24 hours. Test organisms were zebra fish (Danio rerio). The test was conducted with a single test concentration of 100 mg/L, as previously conducted test with algae and Daphnia magna had endpoint values above 100 mg/L.
The test was performed using 7 litre glass vessels filled with 5 litres of test solution and seven fish per group. The temperature during the test was 22 ±1oC and was performed under normal laboratory illumination with a light:dark cycle of 16:8 hours. At test initiation, test renewal, and test termination the temperature, pH and oxygen were measured.
No mortalities or visible abnormalities were observed on any individuals in test concentrations of 100 mg/L test substance. The NOEC was therefore determined to be 100 mg/L and the LC50 was determined to be >100 mg/L.
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