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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

EC10 (activated sludge, 3h, OECD209): 1000 mg/L
EC50 (activated sludge, 3h, OECD209): 1000 mg/L
NOEC (activated sludge, 3h, OECD209) > 1000 mg/L

Key value for chemical safety assessment

EC50 or LC50 for microorganisms:
1 000 mg/L
EC10, LC10 or NOEC for microorganisms:
1 000 mg/L

Additional information

A GLP study conducted according to OECD 209 and EU C11 is available.

Because volatility of the test item could not be excluded, the experiment was performed in closed Schott flasks without aeration and with analytical determination of the content of test item in the liquid phase at the beginning and at the end of the test, as described in the OECD guideline. The study was performed using five concentrations, ranging from 1000 to 10 mg/L nominal concentration. The dry matter of the activated sludge was determined as 2.04 g suspended solids/L, giving a concentration of 1 .02 g suspended solids/L in the test. EC50 of the positive control was determined as 7.8 mg/L (95% confidence interval: 5.2 — 50 mg/L), which lies within the demanded range of 2 —25 mg/L. Because of slow dissolution of test item, the measured concentrations at the end of the test were much higher than at the beginning. At no test item concentration, any inhibition effect could be observed.