Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1 (reliable without restriction)

Data source

Reference Type:
study report
Report date:

Materials and methods

Test guideline
no guideline followed
Principles of method if other than guideline:
The study was performed according to the Corning Hezleton Definitive Protocol. The determination of the dissociation constat (pKa) was carried out by potentiometric titration.
GLP compliance:

Test material

Results and discussion

Dissociating properties:
not determined

Any other information on results incl. tables

It was not possible to calculatethe pKa value with any degree of accuracy because precipitation of the test substance occured. The color transition observed to occur between pH 10 and pH 12 inpure dioxane, indicated that the ionization values was probably close to pka ~ 11 in pure dioxane. Hence, it is estimated that the aqueous pKa ~ 10.5 +/- 0.5

Applicant's summary and conclusion