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Environmental fate & pathways

Adsorption / desorption

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Reference
Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC estimation method
Media:
soil/sewage sludge
Radiolabelling:
no
Details on study design: HPLC method:
HPLC parameters:
- HPLC system: Agilent Technologies 1050/1100, incorporating autosampler and workstation
- Column: Hypersil Gold CN (150 x 4.6 mm id)
- Column temperature: 35 degrees C
- Mobile phase: methanol:water (55:45 v/v_
- pH of mobile phase: 7.0 adjusted with 0.1M sodium hydroxide
- Flow-rate: 1.0 ml/min
- Injection volume: 10 ul
- UV detector wavelength: 210 nm
Type:
Koc
Value:
177.83
Temp.:
35 °C
Remarks on result:
other: Assumed to have been determined at NTP
Type:
log Koc
Value:
2.25
Temp.:
35 °C
Remarks on result:
other: Assumed to have been determined at NTP
Details on results (HPLC method):
See table 1 (in 'remarks and results including tables and figures' field) for retention times, capacity factors and log Koc values for each sample.
Transformation products:
not measured

Table 1. Retention time, capacity factors and log Koc values for each sample.

Injection Retention time (minutes) Capacity factor (k) Log K Log10Koc Mean Log10Koc
1 2.939 0.425 -0.372 2.25 2.25
2 2.938 0.424 -0.372 2.25
Validity criteria fulfilled:
yes
Conclusions:
Under the conditions of this study, the adsorption coefficient of the test item is 177.83 (log koc = 2.25)

Description of key information

The adsorption coefficient (Koc) was determined by application of EC Method C19/OECD 121 (HPLC method).

Key value for chemical safety assessment

Koc at 20 °C:
177.83

Additional information

Under the conditions of this study, the adsorption coefficient was 177.83: Log Koc = 2.25 (determined at 35 degrees C using HPLC).

[LogKoc: 2.25]