Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Adequacy of study:
other information

Data source

Reference
Reference Type:
publication
Title:
Ethylene Oxide Allergy in Patients on Hemodialysis Waiting for Kidney Transplantation: Logistical Nightmare or Challenge? A Case Report.
Author:
D. Monbaliu et al.
Year:
2010
Bibliographic source:
Transplantation Proceedings 42, 4375 - 4377

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethylene oxide
EC Number:
200-849-9
EC Name:
Ethylene oxide
Cas Number:
75-21-8
Molecular formula:
C2H4O
IUPAC Name:
oxirane

Results and discussion

Applicant's summary and conclusion

Conclusions:
The authors concluded: When ethylene oxide-sensitized patients with chronic kidney disease stage V are considered for transplantation, the surgery represents a substantial risk to induce a severe allergic anaphylactic reaction. Therefore, quality care in full knowledge of the risk should be offered to these patients. At the same time, it may be possible that EO allergy could be regarded as a relative contra-indication for kidney transplantation in some centers. To our surprise, no reports regarding kidney transplantation in EO-sensitized patients have been published before now.