Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-483-3 | CAS number: 141-43-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Acutely harmful to aquatic invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 27 mg/L
Additional information
The acute toxicity to aquatic invertebrates was tested in several studies. The key study investigating the immobilisation of Daphnia magna was conducted according to OECD 202 and ASTME-729 (P&G, 2012). The study was conducted under GLP and with analytical monitoring. The 48 -h EC50 was determined to be 27.04 mg/L (geometric mean). This value indicates that 2 -aminoethanol is acutely harmful to aquatic invertebrates.
Further studies support this conclusion:
In an acute immobilization study according to EU method C.2 under static conditions with analytical monitoring the immobilization of Daphnia magna was investigated. The 48 -h EC50 was determined to be 65 mg/L (measured; Huels, 1997). In a semi-static Daphnia magna immobilisation test according to OECD 202 and under GLP with analytical monitoring, the 48 -h EC50 was 97.26 mg/L (nominal, analytically verified; NITE, 1997). In a further study with Daphnia magna, the 48 -h EC50 was determined to be 32.6 mg/L. However, the test was performed according to a lab procedure which was not further specified in the report. Information on test performance and analytical monitoring are lacking (UCC, 1988).
The effect of MEA on Daphnia magna was studied according to an Environment Canada method (PTAC, 2006). Neonates were exposed to a series of 5 test concentrations and observed over 48 h (mortality). The test concentrations were analytically verified. The 48-h LC50 was determined to be 66.7 mg/L (95% CL: 60.1 -74.1 mg/L; nominal).
Libralato et al. (2010) tested a saline species (Artemia franciscana). The 24 -h EC50 was determined to be 43 mg/L and is within the same range as the freshwater data for 2 -aminoethanol.
The effect of MEA on Hyalella azteca was studied according to an Environment Canada method (PTAC, 2006). 50 animals were exposed to a series of 5 test concentrations and observed over 96 h and dead neonates counted after 48 and 96 h. The test concentrations were analytically verified. The 96 -h LC50 was determined to be 170 mg/L (95% CL: 163 -177 mg/L; nominal).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.