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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010-04-20
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
other: DIN EN ISO/IEC 17025
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution
Specific details on test material used for the study:
Purity: 98.8 %
Batch no. 11191230
Percentile:
other: Mean
Mean:
926.2 µm
St. dev.:
469.6
Percentile:
D90
Mean:
1 644 µm
Remarks on result:
other: St.dev. not given
Percentile:
D50
Mean:
967 µm
Remarks on result:
other: St.dev. not given
Percentile:
D10
Mean:
348 µm
Remarks on result:
other: St.dev. not given
Percentile:
other: D1.15
Mean:
ca. 47.94 µm
Remarks on result:
other: A proportion of 1.15 % of the particles have an average particle size of 47.94 µm

 

Particle size [µm]

Proportion [%]

1st measurement

47.94

1.23

2nd measurement

47.94

1.19

3rd measurement

47.94

1.04

Average

47.94

1.15
Conclusions:

The particle size distribution (volume distribution) of methacrylamide was measured by laser diffraction with dry dispersing.
The dustiness of the substance is low.
However, as a significant proportion of particles (> 1 %) have a diameter below 50 µm, inhalation is considered as a relevant exposure pathway.
Executive summary:

The particle size distribution (volume distribution) of methacrylamide was measured by laser diffraction with dry dispersing.

The average of three measurements is: d90: 1644 µm; d50: 967 µm; d10: 348 µm;

A proportion of 1.15 % has a diameter of 47.94 µm (d1.15: 47.94 µm).

The dustiness of the substance is low.

However, as a significant proportion of particles (> 1 %) have a diameter below 50 µm, inhalation is considered as a relevant exposure pathway (cf ECHA Guidance R.14, page 110).

Description of key information

The average of three measurements is: d90: 1644 µm; d50: 967 µm; d10: 348 µm;

A proportion of 1.15 % has a diameter of 47.94 µm (d1.15: 47.94 µm).

The dustiness of the substance is low.

However, as a significant proportion of particles (> 1 %) have a diameter below 50 µm, inhalation is considered as a relevant exposure pathway (cf ECHA Guidance R.14, page 110).

Additional information