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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Determination of the potential for bioaccumulation follows Guidance on Information Requirements and Chemical Safety Assessment Chapter R.16: Environmental Exposure Estimation (ECHA, 2012). Chapter R.16 and REACH Annex IX states that there may be bioaccumulation potential if log Kow is >3. Experimentally measured log Kow for Hydrotrope Category substances range between -3.18 to 0.07. The likelihood of bioaccumulation is very low and the requirement for further testing is waived.

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Determination of the potential for bioaccumulation follows Guidance on Information Requirements and Chemical Safety Assessment Chapter R.16: Environmental Exposure Estimation (ECHA, 2012). Chapter R.16 and REACH Annex IX states that there may be bioaccumulation potential if log Kow is >3. Experimentally measured log Kow for Hydrotrope Category substances range between -3.18 to 0.07. The likelihood of bioaccumulation is very low and the requirement for further testing is waived.

In addition, experimental studies carried out in accordance with OECD Guideline 305C were considered to be reliable (Klimisch 2) in the evaluation of two hydrotrope category substances by the OECD SIDS SIAM Report (2006) authors. Using freshwater cyprinus species fish, the flow-through aquatic test determined bioconcentration factors from both experiments to be <2.3. The requirement for bioaccumulation testing in the aquatic environment (REACH Annex IX) is waived based on the weight of evidence from the measured Log Kow values (between -3.18 and 0.07) and the two bioaccumulation in fish studies with reported BCF of less than 2.3. The likelihood of bioaccumulation is considered to be very low.